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Medchemexpress LLC CYM-5478 | 870762-83-7 | 99.9% | 388.38 | 25 MG
Supplier: Medchemexpress LLC 25MGHY111253
CYM-5478 is a potent and highly selective S1P2 agonist with an EC50 of 119 nM in a TGFα-shedding assay. It protects neural-derived cell lines against Cisplatin toxicity.
- Potent and highly selective S1P2 agonist
- Protects neural-derived cell lines against Cisplatin toxicity
- Attenuates Cisplatin-induced caspase 3/7 activity
- Attenuates increase of ROS in C6 cells exposed to Cisplatin
- Protects against Cisplatin-mediated ototoxicity
- Protects against loss of hair cell viability in a zebrafish model
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