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Medchemexpress LLC Cyproheptadine (hydrochloride) | 969-33-5 | 99.3% | 250 MG
SDP

Supplier:  Medchemexpress LLC 250MGHYB1165R

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Cyproheptadine hydrochloride is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. It also exhibits antiplatelet and thromboprotective activities, making it suitable for the research of thromboembolic disorders.

  • Potent and orally active 5-HT2A receptor antagonist.
  • Possesses antidepressant and antiserotonergic effects.
  • Demonstrates antiplatelet and thromboprotective activities.
  • Useful for research into thromboembolic disorders.
  • Inhibits serotonin-enhanced ADP-induced mouse platelet aggregation in vitro.
  • Inhibits 15 μM serotonin-enhanced ADP-induced (1 μM) tyrosine phosphorylation in platelets in vitro.
  • Inhibits human platelet PS exposure (Annexin V), P-selectin, and GPIIb-IIIa (PAC-1 binding) activation in vitro.
  • Exerts thromboprotective properties in vivo (in C57BL/6 mice at 1 mg/kg; i.p.; daily, for 5 days).

Catalog No. 50-004-14333


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