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Medchemexpress LLC D-3 | 1967815-98-0 | 99.5% | 5 MG
Supplier: Medchemexpress LLC HYP22865MG
D-3 is a phosphorpeptide that acts as an efficient, simple, and specific iPSC-eliminating agent. It is intended for research use only. It prevents residual iPSC-induced teratoma formation in a mouse tumorigenicity assay and induces a significant loss of viability in 201B7 cells with a half-maximal inhibitory concentration of 192.3 ± 57.4 μM.
- Acts as an efficient, simple, and specific iPSC-eliminating agent.
- Prevents residual iPSC-induced teratoma formation in a mouse tumorigenicity assay.
- Induces significant loss of viability in 201B7 cells.
- Activates eIF2a, p38, and p44/42 MAPK, which are pathways responsive to cellular stress.
- Increases the number of apoptotic and dead cells.
- Has minimal effects on various non-iPSCs, such as hepatocytes and neurons.
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