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Medchemexpress LLC Dabigatran ethyl ester hydrochloride | 211914-50-0 | 99.4% | C27H30ClN7O3 | 1 ML
Supplier: Medchemexpress LLC HY7752110MM/1ML
Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM. It also functions as a thrombin inhibitor. The ethyl ester group enhances interaction with hydrophobic amino acids, contributing to its higher affinity for both thrombin and NQO2 compared to Dabigatran. This compound is a selective, reversible, and potent thrombin inhibitor, orally available as the prodrug, dabigatran etexilate.
- Potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2)
- Thrombin inhibitor
- Higher affinity for thrombin and NQO2 compared to Dabigatran
- Selective and reversible thrombin inhibitor
- Orally available as the prodrug dabigatran etexilate
- For research use only
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