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Medchemexpress LLC Dac590 | 3084407-00-8 | 96.15% | 390.79 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1749795MG

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Dac590 is an orally active FTO inhibitor. It exhibits a robust antiproliferative effect on AML cells, inducing apoptosis and cell cycle G1 arrest by inhibiting oncogenic FTO signaling. Dac590 significantly inhibits tumor growth and prolongs survival without observed toxicity in acute myeloid leukemia (AML) xenograft mice models, and shows a synergistic effect when combined with Decitabine.

  • Orally active FTO inhibitor
  • Robust antiproliferative effect on AML cells
  • Induces apoptosis and cell cycle G1 arrest
  • Inhibits oncogenic FTO signaling
  • Significantly inhibits tumor growth
  • Prolongs survival in AML xenograft models
  • Shows synergistic effect with Decitabine

Catalog No. 50-003-86900


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