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Medchemexpress LLC Dactolisib | 915019-65-7 | >99% | C30H23N5O | 200 MG
Supplier: Medchemexpress LLC HY50673200MG
Dactolisib (BEZ235) is an orally active, dual pan-class I PI3K, and mTOR kinase inhibitor. It inhibits both mTORC1 and mTORC2, demonstrating potent activity against PI3K in an ATP competitive manner. This compound is known to reduce phosphorylation levels of mTOR activated kinase p70S6K and S235/S236P-RPS6.
- Dual pan-class I PI3K and mTOR kinase inhibitor
- Orally active
- Inhibits both mTORC1 and mTORC2
- Potently inhibits PI3K in an ATP competitive manner
- Effective in reducing phosphorylation levels of p70S6K and S235/S236P-RPS6
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