Medchemexpress LLC Dactolisib (Tosylate) | 1028385-32-1 | C37H31N5O4S | 1 ML

Supplier:  Medchemexpress LLC HY1517410MM/1ML

Dactolisib Tosylate is a dual PI3K and mTOR kinase inhibitor. It effectively blocks the dysfunctional activation of the PI3K pathway, inducing G1 arrest in human tumor cell lines. This compound is well tolerated in vivo, induces disease stasis when administered orally, and enhances the efficacy of other anticancer agents.

• Dual PI3K and mTOR kinase inhibitor
• Inhibits both mTORC1 and mTORC2
• Induces G1 arrest in human tumor cell lines
• Active against mutant PI3Kα
• Reduces cell proliferation in PTEN-null cell lines
• Well tolerated in vivo
• Enhances efficacy of other anticancer agents

Catalog No. 50-003-74850