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Medchemexpress LLC Dactolisib (tosylate) | 1028385-32-1 | C37H31N5O4S | 200 MG
Supplier: Medchemexpress LLC HY15174200MG
Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor. It inhibits mTORC1 and mTORC2, and is active against mutant PI3KαE545K or PI3KαH1047R. This compound effectively and specifically blocks dysfunctional activation of the PI3K pathway, inducing G1 arrest in human tumor cell lines. It is well tolerated and enhances the efficacy of other anticancer agents.
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