Apexbio Technology LLC DAMGO 78123-71-4 10mg

Supplier:  Apexbio Technology LLC B662110

DAMGO (CAS 78123-71-4) is a peptide agonist selective for the -opioid receptor showing high affinity with a Ki of approximately 1 18 nM compared to markedly lower affinities for - and -opioid receptors -opioid receptors are class A G protein-coupled receptors that transduce signals via intracellular G protein cascades and regulate multiple cellular processes commonly studied for their role in pain pathways DAMGO activates -opioid signaling as demonstrated by increased [ 35S]GTP S binding in cell membrane assays (EC50 222 nM) inhibition of muscle contractions in mouse vas deferens (EC50 238 47 nM) and reduction of visceral pain responses in rat models Therefore DAMGO serves as an important research tool for investigating -opioid receptor biology and analgesia

Catalog No. 50-000-63734