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Selleck Chemical LLC Danusertib (PHA-739358) 50mg 827318-97-8
Supplier: Selleck Chemical LLC S110750MG
Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Danusertib induces apoptosis, cell cycle arrest, and autophagy. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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