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Apexbio Technology LLC Daptomycin 103060-53-3 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC A12065.1
Daptomycin is a calcium-dependent cyclic lipopeptide antibiotic exhibiting bactericidal activity against a range of Gram-positive bacteria including antibiotic-resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA) vancomycin-intermediate (VISA) and vancomycin-resistant S aureus (VRSA) Its antimicrobial mechanism involves calcium-mediated insertion into bacterial cell membranes disrupting membrane integrity and depolarizing membrane potential resulting in rapid bacterial cell death Daptomycin is frequently employed in microbiological and pharmacological research to investigate antibiotic resistance mechanisms and evaluate bacterial susceptibility profiles generally showing antibacterial IC50 values in the low micromolar ( M) range
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