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Apexbio Technology LLC Darunavir Ethanolate 635728-49-3 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B49505.1
Darunavir Ethanolate (CAS 635728-49-3) is a small-molecule inhibitor targeting HIV protease It is designed to inhibit HIV protease disrupting the proteolytic processing of viral polyproteins required for HIV replication Darunavir Ethanolate exerts its biological activity primarily through selective binding to the active site of HIV protease In cell-based studies it demonstrates inhibitory activity against both wild-type and protease inhibitor-resistant HIV strains with an IC50 value of 1 nM for wild-type HIV-1 protease Based on these pharmacological properties Darunavir Ethanolate holds research potential in studies of HIV/AIDS particularly for investigating antiviral resistance mechanisms and evaluating HIV replication inhibition in vitro
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