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Medchemexpress LLC Datelliptium chloride | 105118-14-7 | 397.94 | 50 MG

Supplier: Medchemexpress LLC HYU0033750MG
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.
- DNA-intercalating agent
- Derived from ellipticine
- Exhibits anti-tumor activities
- Shows significantly cytotoxic effects in suspension and primary cultures of rat hepatocytes (100 μM after 2 hr treatment)
- Mobilizes glycogen in rat systems in vitro concentration-dependently
- Leads to a concentration-dependent decrease in gluconeogenesis from lactate in cells
- Datelliptium acetate (a related form) is selectively cytotoxic for solid tumors over leukemia L1210
- Datelliptium acetate shows potent inhibitory activities in vivo against various murine solid tumors upon intravenous administration
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