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Medchemexpress LLC Dbco-nhco-peg2-biotin | 2989400-08-8 | 97.1% | 661.81 g·mol⁻1 | C35H43N5O6S | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1359395MG

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DBCO-NHCO-PEG2-Biotin is a PEG-based click-chemistry linker that introduces a biotin tag to azide-functionalized targets via copper-free strain-promoted alkyne-azide cycloaddition (SPAAC). It contains a dibenzocyclooctyne reactive group and a PEG2 spacer terminating in biotin, and is supplied as a small-mass reagent for bioconjugation, pull-down assays, and linker assembly. Purity reported ~97.1%; molecular weight 661.81 g·mol⁻1.

  • Facilitates copper-free biotinylation of azide-containing biomolecules.
  • Provides a short PEG2 spacer for improved solubility and reduced steric hindrance.
  • Suitable for pull-downs, affinity capture, and proteomics workflows.
  • Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC); no copper catalyst required.
  • Supplied in small quantities for research and conjugation optimization.

Catalog No. 50-002-22091


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