Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC DBCO-PEG2-acid | 2304558-25-4 | >=95.0% | C26H28N2O6 | 50 MG
Supplier: Medchemexpress LLC HY14026650MG
DBCO-PEG2-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs themselves are composed of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein, allowing PROTACs to exploit the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features a DBCO group for SPAAC
- Reacts with azide-containing molecules
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?