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Medchemexpress LLC Dbco-(PEG2-VC-PAB-MMAE)2 | 2259318-55-1 | 99.2% | 2835.50 g/mol | C149H224N22O32 | 100 MG
Supplier: Medchemexpress LLC HY126690100MG
DBCO-(PEG2-VC-PAB-MMAE)2 is a drug-linker conjugate and click-chemistry reagent used for preparing antibody-drug conjugates and other azide-based bioconjugates. It combines a DBCO clickable handle, a PEG2 spacer, a Val-Cit protease-cleavable dipeptide, a PAB self-immolative spacer, and an MMAE cytotoxic payload.
- Provides strain-promoted alkyne-azide cycloaddition (SPAAC) reactivity for conjugation to azide-tagged molecules.
- Val-Cit linker enables protease-mediated intracellular release of the MMAE payload.
- Supplied with analytical documentation, including HNMR, RP-HPLC, MS, COA, and SDS.
- Available in multiple pack sizes, including a 100 mg quantity for preparative use.
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