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Medchemexpress LLC DBCO-PEG3-TCO | 2755573-20-5 | 98.0% | 631.76 | C36H45N3O7 | 25 MG
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Supplier:  Medchemexpress LLC HY13342825MG

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DBCO-PEG3-TCO is a heterobifunctional PEG-based linker used in bioconjugation and antibody-drug conjugate (ADC) synthesis. It contains a dibenzocyclooctyne (DBCO) moiety for strain-promoted alkyne-azide cycloaddition (SPAAC) with azides, and a trans-cyclooctene (TCO) moiety for inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazines. Typical applications include ADC linker development and click-chemistry bioconjugation.

  • Non-cleavable 3 unit PEG linker used in ADC synthesis.
  • Supports strain-promoted alkyne-azide cycloaddition (SPAAC) via a DBCO group.
  • Enables inverse electron-demand Diels-Alder (iEDDA) reactions via a TCO group.
  • High purity suitable for research applications.

Catalog No. 50-002-03692


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