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Medchemexpress LLC Dbco-PEG3-TCO | 2755573-20-5 | 98.0% | 631.76 g·mol⁻¹ | C36H45N3O7 | 50 MG

Supplier: Medchemexpress LLC HY13342850MG
DBCO-PEG3-TCO is a heterobifunctional click-chemistry linker used for bioconjugation and antibody-drug conjugate (ADC) synthesis. It contains a dibenzocyclooctyne (DBCO) group for strain-promoted alkyne-azide cycloaddition and a trans-cyclooctene (TCO) group for rapid tetrazine ligation, joined by a three-unit polyethylene glycol (PEG3) spacer, enabling aqueous-phase conjugation and improved solubility.
- Facilitates catalyst-free azide-alkyne cycloaddition and tetrazine ligation
- Heterobifunctional design enables orthogonal dual conjugation strategies
- PEG3 spacer improves solubility and reduces steric hindrance
- High purity suitable for bioconjugation workflows
- Available in small milligram pack sizes for research use
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