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Medchemexpress LLC Dbco-PEG4-VA-PBD | 2241644-09-5 | 99.7% | 1430.60 | C80H87N9O16 | 1 MG
Supplier: Medchemexpress LLC HY1334331MG
DBCO-PEG4-VA-PBD is a drug-linker conjugate intended for antibody-drug conjugate (ADC) conjugation workflows. The molecule features a DBCO reactive group for strain-promoted alkyne-azide cycloaddition (SPAAC), a PEG4 spacer, a valine-alanine protease-cleavable linker, and a pyrrolobenzodiazepine (PBD) cytotoxic payload. Supplied as a solid for research use.
- Contains DBCO group for SPAAC click chemistry
- Includes PEG4 spacer for improved solubility
- Valine-alanine cleavable linker enables intracellular payload release
- PBD payload for potent cytotoxic activity
- Supplied as 1 mg solid; purity reported ~99.7%
- Store at -80°C under nitrogen; shipped on dry ice
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