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Medchemexpress LLC Dbco-PEG4-VC-PAB-MMAE | 2129164-91-4 | 99.2% | 1658.03 | C88H128N12O19 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY136314100MG

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DBCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate combining a DBCO click handle, a PEG4 spacer, a valine-citrulline-p-aminobenzyl cleavable linker, and the cytotoxic monomethyl auristatin E payload. It is intended for research use in synthesizing antibody-drug conjugates via strain-promoted alkyne-azide cycloaddition.

  • Used for strain-promoted alkyne-azide cycloaddition (SPAAC) conjugation.
  • Contains a PEG4 spacer for increased hydrophilicity.
  • Includes a valine-citrulline-p-aminobenzyl cleavable linker for intracellular release.
  • Incorporates monomethyl auristatin E as the cytotoxic payload.
  • High purity (99.18%).
  • Soluble in DMSO at 150 mg/mL; may require ultrasonic assistance.
  • Supplied as a powder; unstable in solution, store at -20°C and prepare fresh solutions.

Catalog No. 50-002-04182


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