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Medchemexpress LLC Dbco-PEG4-VC-PAB-MMAE | 2129164-91-4 | 99.2% | 1658.03 g/mol | C88H128N12O19 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY13631450MG

Encompass_Preferred

Drug-linker conjugate used for antibody-drug conjugate (ADC) research that couples a DBCO clickable handle and a PEG4 spacer to a valine-citrulline cleavable linker with a p-aminobenzyl self-immolative spacer and the cytotoxic payload monomethyl auristatin E (MMAE). Supplied as a solid for conjugation via strain-promoted alkyne-azide cycloaddition (SPAAC) to azide-functionalized biomolecules.

  • Enables SPAAC click conjugation to azide-containing biomolecules.
  • Includes Val-Cit cleavable linker for intracellular payload release.
  • Contains PEG4 spacer to improve hydrophilicity and reduce aggregation.
  • Provided as a solid suitable for storage and DMSO formulation.
  • High reported purity for reliable conjugation performance.

Catalog No. 50-002-03304


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