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Medchemexpress LLC DC-BPi-11 (hydrochloride) | 97.0% | C20H24ClN5O2S | 100 MG
Supplier: Medchemexpress LLC HY141703A100MG
DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), showing an IC50 value of 698 nM. It demonstrates significant inhibition against leukemia cell proliferation in human leukemia MV-4-11 cells with an EC50 value of 120 nM, while having minimal effects on normal cells, suggesting a favorable safety profile.
- Inhibits bromodomain PHD finger transcription factor (BPTF)
- Significantly inhibits leukemia cell proliferation
- Decreases downstream oncogene expression
- Dose-dependently decreases c-Myc protein level
- Minimal effects on normal cells
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