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Medchemexpress LLC Dcemm2 | 296771-07-8 | 99.3% | 370.82 g/mol | C16H11ClN6OS | 5 MG
Supplier: Medchemexpress LLC HY1449715MG
dCeMM2 is a molecular glue-type degrader that induces ubiquitination and proteasomal degradation of cyclin K by promoting interaction between CDK12-cyclin K and a CRL4B E3 ligase complex. It inhibits CDK12/13 activity and is intended for cell-based research applications.
- Promotes ubiquitination and degradation of cyclin K in cells
- Inhibits CDK12/13 enzymatic activity with selectivity over CDK7
- Demonstrated cellular activity in KBM7 and HEK assays
- High purity suitable for biochemical and cell assays
- Soluble in DMSO for in vitro preparations
- Stable as powder at -20°C or 4°C with defined storage times
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