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ABclonal Technology DDX3 Rabbit PolymAb
SDP

Supplier:  ABclonal Technology A25442PM20UL

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This gene encodes a protein in the DEAD-box family characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif with ATP-dependent RNA helicase activity Unlike most DEAD-box helicases this protein exhibits RNA- and DNA-stimulated ATPase activity It contains multiple conserved domains and functions in both the nucleus and cytoplasm In the nucleus it is involved in transcription regulation mRNP assembly pre-mRNA splicing and mRNA export In the cytoplasm it participates in translation cellular signaling and viral replication Misregulation of this gene is linked to tumorigenesis The gene has a paralog on the Y chromosome and pseudogenes on chromosomes 4 and X Alternative splicing results in multiple transcript variants

Catalog No. 50-000-11074


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