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CPC Scientific H-Asp-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific DEFS007C
This peptide contain 6 conserved disulfide-linked cysteines. In vitro, it has a prominent antimicrobial activities against bacteria, fungi, and certain enveloped viruses. In addition, human and rabbit defensins exert potent cytotoxicity in vitro against various mammalian tumor cells.SEQUENCE: H-Asp-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH (trifluoroacetate salt)(Cys2 and Cys30/Cys4 and Cys19/Cys9 and Cys29 Bridge)ONE-LETTER SEQUENCE: DCYCRIPACIAGERRYGTCIYQGRLWAFCC(Cys2 and Cys30/Cys4 and Cys19/Cys9 and Cys29 Bridge)MOLECULAR FORMULA: C151H222N44O40S6MOLECULAR WEIGHT: 3486.09STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [136661-76-2]SYNONYMS: RESEARCH AREA: AntimicrobialCATEGORY: Defensins REFERENCES:P.A.Raj et al., Biochem. J., 347, 633 (2000)F.T.Lundy et al., Oral Oncol., 40, 139 (20
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