Medchemexpress LLC Deltonin | 55659-75-1 | 1 MG

Supplier:  Medchemexpress LLC HYN22831MG

Deltonin is a steroidal saponin isolated from *Dioscorea zingiberensis* that exhibits antitumor activity by inhibiting ERK1/2 and AKT activation. In vitro studies demonstrate its ability to inhibit the proliferation of various colon cancer cell lines and induce apoptosis. In vivo, Deltonin has been shown to reduce tumor growth and inhibit tumor angiogenesis, contributing to increased survival rates in animal models.

• Steroidal saponin isolated from *Dioscorea zingiberensis*
• Exhibits antitumor activity
• Inhibits ERK1/2 and AKT activation
• Inhibits proliferation of colon cancer cell lines
• Causes G2-M phase arrest and induces apoptosis
• Decreases phosphorylation of AKT and ERK1/2 levels
• Inhibits proliferation and induces apoptosis with ROS production
• Reduces tumor growth in mice
• Inhibits tumor angiogenesis in mice

Catalog No. 50-004-21395