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Medchemexpress LLC Dendrogenin A | 1191043-85-2 | 96.7% | 513.80 | 1 MG
Supplier: Medchemexpress LLC HY1491321MG
Dendrogenin A is a ligand for liver X receptor (LXR) that induces the expression of sodium/iodine symporter, increasing iodine uptake. It also induces cell differentiation of MCF-7 cells, reactivates the function of lactating cells, and influences thyroid hormone generation by inducing expressions of TSH receptor, thyroid peroxidase, and thyroglobulin. Dendrogenin A exhibits cytotoxicity in cancer cells B-CPAP and 8505c, and arrests the cell cycle at the G0/G1 phase.
- Ligand for liver X receptor (LXR)
- Induces expression of sodium/iodine symporter
- Increases iodine uptake
- Induces cell differentiation of MCF-7 cells
- Reactivates function of lactating cells
- Affects thyroid hormone generation
- Exhibits cytotoxicity in cancer cells
- Arrests cell cycle at G0/G1 phase
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