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Medchemexpress LLC Dendrophenol | 108853-14-1 | 1 MG
Supplier: Medchemexpress LLC HYN60311MG
Dendrophenol (Moscatilin) is an NF-κB inhibitor that inhibits inflammation. It exerts a potent cytotoxic effect against tumor cells, inducing cell cycle arrest and apoptosis, and demonstrates antitumor activity. Additionally, Dendrophenol can inhibit vascular calcification by suppressing the activation of WNT3/β-catenin.
- Inhibits expression of COX-2, iNOS, HIF-1α, and NF-κB in LPS-treated macrophages.
- Exerts cytotoxic effects against tumor cell lines and causes cell G2 phase arrest.
- Reduces calcium deposition via the WNT3/β-catenin pathway.
- Induces apoptosis in human colon cancer cell HCT-116.
- Shows beneficial effects in a mouse model of vascular calcification.
- Exhibits antitumor effects in a mouse tumor model.
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