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Medchemexpress LLC Denfivontinib | 1457983-28-6 | MFCD28167815 | 98.0% | 521.41 g/mol | C25H25BrN6O2 | 50MG
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Supplier:  Medchemexpress LLC HY1233350MG

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Denfivontinib (G-749) is a potent, orally active ATP-competitive inhibitor of FMS-like tyrosine kinase 3 (FLT3) developed for research applications, including studies of drug resistance in acute myeloid leukemia (AML). It inhibits wild-type and mutant FLT3 at sub-nanomolar concentrations and is supplied as a solid research compound.

  • Potent FLT3 inhibition: IC50 0.4 nM (wild type), 0.6 nM (D835Y)
  • CAS number: 1457983-28-6
  • Chemical formula: C25H25BrN6O2
  • Molecular weight: 521.41 g/mol
  • Purity: 98.0%
  • Physical form: white to off-white solid; hydrochloride salt available
  • Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years)
  • Intended use: research tool compound for AML and kinase studies

Catalog No. 50-002-39548


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