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Medchemexpress LLC Denifanstat | 1399177-37-7 | 99.6% | 439.55 | 25 MG
Supplier: Medchemexpress LLC 25MGHY112829
Denifanstat (TVB-2640) is an orally active, potent Fatty Acid Synthase (FASN) inhibitor (IC50 of 0.052 μM, EC50 of 0.072 μM) with potential for fatty liver disease and cancer research. Also known as FASN-IN-2 and ASC-40, it has a molecular weight of 439.55 and formula C27H29N5O. This white to off-white solid is for research use only.
- Orally active and potent fatty acid synthase (FASN) inhibitor.
- IC50 of 0.052 μM and EC50 of 0.072 μM for FASN inhibition.
- Potential for fatty liver disease and cancer research.
- Prevents palmitoylation of SARS-CoV2 spike protein.
- Suppresses SARS-CoV-2 virus replication, reduces weight loss, and prolongs survival after SARS-CoV-2 infection.
- Used in published research for cancer and SARS-CoV-2 studies.
- Undergoing clinical trials for MASH/NASH, acne vulgaris, and various cancers.
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