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Medchemexpress LLC Desloratadine | 100643-71-8 | 100.0% | 10 G
Supplier: Medchemexpress LLC HYB053910G
Desloratadine is an orally active and selective H1 receptor antagonist (Ki=0.9 nM) with anti-inflammatory and anti-allergic activities. It inhibits the release of histamine and LTC4 from human basophils, modulating regulatory signals for IL-4 and IL-13 production. This compound effectively alleviates seasonal allergic rhinitis (SAR) symptoms in patients with concurrent asthma, making it valuable for research into allergic rhinitis and chronic idiopathic urticaria.
- Orally active and selective H1 receptor antagonist
- Exhibits anti-inflammatory and anti-allergic properties
- Inhibits histamine and LTC4 release from basophils
- Modulates IL-4 and IL-13 production
- Alleviates seasonal allergic rhinitis symptoms
- Used in studies for allergic rhinitis and chronic idiopathic urticaria
- Appears as an off-white to light yellow solid
- Molecular weight: 310.83
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