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Medchemexpress LLC Desonide | 638-94-8 | 99.2% | 200 MG
Supplier: Medchemexpress LLC HYB0248200MG
Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on the glucocorticoid receptor. It can also specifically bind to the mutant huntingtin protein (mHTT), reducing the level and toxicity of mHTT. Desonide can be used in the research of Huntington's disease and inflammatory diseases such as atopic dermatitis.
- Non-fluorinated corticosteroid anti-inflammatory agent
- Modulates glucocorticoid receptor activity
- Specifically binds to mutant huntingtin protein (mHTT)
- Reduces mutant huntingtin protein (mHTT) levels and toxicity
- Used in Huntington's disease research
- Used in inflammatory disease research, such as atopic dermatitis
- Inhibits mHTT-induced cytotoxicity
- Reduces apoptotic signals and improves cell survival
- Demonstrates therapeutic effects in Huntington's disease mouse models
- Rescues behavioral deficits and lowers mHTT aggregates
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