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Medchemexpress LLC Dexrazoxane | 24584-09-6 | 99.88% | 10 MM 1 ML
Supplier: Medchemexpress LLC HYB058110MM/1ML
Dexrazoxane is an intracellular iron chelating agent that reduces the formation of superoxide radicals. It exhibits cardioprotective, anti-inflammatory, antioxidant, anti-tumor, and neuroprotective activities. It inhibits ferroptosis of H9c2 cells by inhibiting HMGB1 and induces DNA damage and apoptosis in human fibrosarcoma cells.
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage for in solvent: -80°C for 6 months, -20°C for 1 month
- Induces DNA breaks, ATF3 accumulation, DNA damage response, and apoptosis in human fibrosarcoma cells
- Inhibits ferroptosis of H9c2 cells by inhibiting HMGB1
- Plays a protective role in rat models of doxorubicin-induced cardiomyopathy
- Provides antioxidant and anti-inflammatory effects in rodent models of Parkinson's disease
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