Medchemexpress LLC DGY-06-116 | 2556836-50-9 | 98.6% | 597.11 | 50 MG

Supplier:  Medchemexpress LLC HY13660550MG

DGY-06-116 is an irreversible, covalent, and selective Src inhibitor with an IC50 of 3 nM. It demonstrates potent antiproliferative effects in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC) cell lines that exhibit SRC activation. This compound effectively induces SRC binding and inhibits SRC signaling in NSCLC cells, and can also inhibit Src for an extended duration in adult C57B6 mice.

• Irreversible covalent, selective Src inhibitor (IC50 of 3 nM)
• Inhibits FGFR1 (IC50 of 8340 nM)
• Exhibits potent antiproliferative effects in NSCLC and TNBC cell lines
• Capable of inducing potent SRC binding and inhibition of SRC signaling in NSCLC cells
• Can inhibit Src for an extended duration in adult C57B6 mice

Catalog No. 50-003-50550