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Medchemexpress LLC DHFR-IN-4 | 2820126-49-4 | C18H21N5O2S | 1 MG

Supplier: Medchemexpress LLC HY1511591MG
DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with an IC50 value of 123 nM. It also exhibits inhibitory activity against EGFR and HER2 with IC50s of 246 nM and 357 nM, respectively, demonstrating remarkable broad-spectrum cytotoxic potency against cancer cells.
- Potent dihydrofolate reductase (DHFR) inhibitor (IC50 = 123 nM)
- Inhibitory activity against EGFR (IC50 = 246 nM) and HER2 (IC50 = 357 nM)
- Remarkable broad-spectrum cytotoxic potency against cancer cells
- Exhibits antiproliferative activity against HepG2, MCF-7, HCT-116, PC3, and HeLa cell lines
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