Medchemexpress LLC Diammonium Glycyrrhizinate | 79165-06-3 | 100 MG

Supplier:  Medchemexpress LLC HYN6804100MG

Diammonium glycyrrhizinate is a substance extracted and purified from a traditional Chinese medicinal herb. It exhibits anti-inflammatory effects, resistance to biologic oxidation, membranous protection, and a weak steroidal action. It acts by downregulating inflammation cytokines, suppressing the NF-κB pathway, and restoring superoxide dismutase. This substance can be utilized as a hepatic protector and is suitable for research in liver diseases.

• Decreases mRNA levels of TNF-α, COX-2, iNOS, and IL-1β
• Increases cell viability in HT22 and SH-SY5Y cell lines
• Attenuates Aβ1-42-induced NF-κB nuclear translocation
• Improves inflammatory indices in ulcerative colitis models
• Inhibits increased ALT and AST levels in liver-injury models
• Decreases epididymal adipose tissues in HFD-fed mice
• Ameliorates liver steatosis and prevents NAFLD development

Catalog No. 50-004-19124