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Medchemexpress LLC Diazinon | 333-41-5 | 99.3% | 100 MG
Supplier: Medchemexpress LLC HYB1113100MG
Diazinon is an orally active, irreversible AChE inhibitor and insecticide that can be absorbed through the digestive system, skin, or respiratory tract. It inhibits AChE, leading to the accumulation of acetylcholine, which overstimulates ACh receptors and affects the nervous system. Diazinon also produces reactive oxygen species (ROS), inducing oxidative stress in various tissues. It is mainly used in agriculture as an insecticide and may affect human and animal health.
- Inhibits cell viability in BRL-3A cells and spleen mononuclear cells.
- Increases ROS generation and lipid peroxidation in BRL-3A cells.
- Induces cell cycle arrest at the G1 phase of SMC cells.
- Affects swimming behavior in Daphnia pulex.
- Causes a decrease in renal reduced glutathione in rats.
- Induces histopathological changes in the thymus and spleen of mice.
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