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Apexbio Technology LLC Dihydrodaidzein 17238-05-0 10mg
Supplier: Apexbio Technology LLC C402010
Dihydrodaidzein (CAS 17238-05-0) is a biologically active metabolite of the soy isoflavone daidzein generated through gut microbial metabolism Acting as an estrogen receptor agonist dihydrodaidzein activates estrogen receptor-mediated processes and has been shown to promote the growth of breast cancer cells in vitro at micromolar concentrations It inhibits proliferation and induces apoptosis in benign prostatic epithelial cells as well as suppresses growth of prostate cancer cell lines In murine models oral administration reduced vascular smooth muscle cell migration and proliferation selectively blocking neointimal hyperplasia Dihydrodaidzein is a valuable tool in studies of phytoestrogen activity hormone-dependent cancers and vascular remodeling
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