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Medchemexpress LLC Dihydroergotoxine (mesylate) | 8067-24-1 | 99.6% | 250 MG
Supplier: Medchemexpress LLC 250MGHYB0799
Dihydroergotoxine mesylate (Ergoloid mesylates) is an α-adrenergic blocking agent. It binds with high affinity to the GABAA receptor-associated Cl- channel and interacts with central dopaminergic and serotonergic receptors. It displays antiproliferative, antihypertensive, and neuroprotective activity.
- Inhibits proliferation of human prostate cancer cell lines.
- Stronger inhibitor of low-Km phosphodiesterase than high-Km phosphodiesterase.
- Prevents delayed neuronal death in gerbil hippocampus.
- Exerts a protective effect on oligemically disturbed brain metabolism.
- Alters sleep-wakefulness cycle by increasing wakefulness.
- Decreases blood pressure in spontaneously hypertensive rats.
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