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Apexbio Technology LLC Diltiazem HCl 33286-22-5 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B20895.1
Diltiazem HCl is a small-molecule inhibitor targeting L-type calcium channels predominantly located on cardiac and vascular smooth muscle cells It is designed to inhibit calcium influx thereby reducing intracellular calcium concentrations and regulating muscle contraction and cardiac conduction Diltiazem HCl exerts its biological activity primarily through blockade of L-type calcium channels resulting in vascular smooth muscle relaxation decreased myocardial contractility slowed cardiac conduction reduced heart rate and coronary artery dilation Based on these pharmacological properties Diltiazem HCl holds research potential in cardiovascular pharmacology specifically for studies investigating mechanisms underlying cardiac arrhythmias ischemic heart conditions hypertension and related therapeutic interventions
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