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Apexbio Technology LLC Diosmetin 520-34-3 200mg

Supplier: Apexbio Technology LLC B5990200
Diosmetin (CAS 520-34-3) is a small molecule flavonoid that functions as an agonist of the aryl hydrocarbon receptor (AHR) a ligand-activated transcription factor involved in the regulation of xenobiotic-metabolizing enzymes In cell-based studies diosmetin dose-dependently increases AHR-mediated transcriptional activation including upregulation of CYP1A1 mRNA and enzymatic activity in MCF-7 cells The compound demonstrates inhibitory effects on CYP1A1 enzyme activity with an IC50 of approximately 30 nM in microsomal assays Diosmetin is utilized in biomedical research to study AHR activation CYP1 enzyme regulation and related cellular responses such as viability and gene expression changes
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