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Medchemexpress LLC Diphenhydramine | 58-73-1 | 99.6% | 1 ML
Supplier: Medchemexpress LLC HYB030310MM/1ML
Diphenhydramine is a first-generation histamine H1-receptor antagonist that also exhibits anti-cholinergic effects. This compound is known for its ability to cross the ovine blood-brain barrier (BBB) and can block NMDA-activated membrane currents, which may contribute to its sedative, analgesic, and memory-related effects.
- First-generation histamine H1-receptor antagonist
- Possesses anti-cholinergic effect
- Can cross the ovine blood-brain barrier
- Targets H1 receptor and NMDA receptor
- Blocks NMDA-activated membrane currents
- May improve kidney injury induced by cisplatin in mice
- Exhibits better oral bioavailability when combined with dimenhydrinate
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