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Cayman Chemical DIphenylenIodonIumchLRIde 10mg
Supplier: Cayman Chemical 8105010 MG
A NOX inhibitor (EC50 = 0.1 µM in HeLa cells); inhibits NOS (IC50 = 0.05 µM in isolated mouse peritoneal macrophages); induces the production of ROS in, and apoptosis of, HUVECs at 10, 50, and 100 µM; inhibits PMA-induced NETosis in isolated human neutrophils at 10 µM; reduces tumor growth in HT-29 and LS 174T colon cancer mouse xenograft models at 2 mg/kg
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