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Apexbio Technology LLC DiSC3(5) 53213-94-8 50mg
Supplier: Apexbio Technology LLC A467250
DiSC3 5 (CAS 53213-94-8) is a fluorescent probe targeting mitochondrial membrane potential and mitochondrial NAD-dependent respiration It is designed to monitor transmembrane potential changes thereby assessing mitochondrial function DiSC3 5 exerts its biological activity primarily through specific interference with mitochondrial NAD-related respiratory pathways In cell-based studies DiSC3 5 demonstrates inhibitory activity with an IC50 value of 8 M in mitochondrial NAD-dependent respiratory systems In the presence of Na /K -ATPase inhibitor ouabain DiSC3 5 induces plasma membrane hyperpolarization in Ehrlich ascites tumor cells Based on these pharmacological properties DiSC3 5 holds research potential in mitochondrial membrane potential detection and cellular bioenergetics studies
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