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Medchemexpress LLC DMA-135 hydrochloride | 2237925-62-9 | MFCD34676484 | 98.0% | 359.81 g/mol | C16H18ClN7O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1459325MG

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DMA-135 hydrochloride is the hydrochloride salt of a small-molecule that targets the internal ribosome entry site (IRES) of enterovirus 71 (EV71). It binds the SLII RNA domain with moderate affinity (KD ≈ 520 nM) and suppresses IRES-dependent translation and viral replication in cell-based studies, making it suitable as a research reagent for antiviral and RNA-ligand interaction studies.

  • Hydrochloride salt of an EV71 IRES-targeting small molecule.
  • Binds SLII RNA domain with KD ≈ 520 nM.
  • Inhibits IRES-dependent translation and replication in cell assays.
  • High purity (~98.0% by HPLC).
  • Available as solid and as 10 mM solution in DMSO for assays.
  • Molecular formula C16H18ClN7O; molecular weight 359.81 g/mol.

Catalog No. 50-002-21336


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