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Medchemexpress LLC Dolcanatide | 1092457-65-2 | 99.2% | 1681.89 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYP34991MG

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Dolcanatide is an orally active agonist of guanylate cyclase-C (GC-C). It exhibits laxative, anti-nociceptive, and anti-inflammatory activities, making it suitable for research related to inflammatory bowel disease.

  • Activates GC-C receptors to stimulate cGMP synthesis in T84 cells.
  • Suppresses lipopolysaccharide-induced paracellular permeability in Caco-2 and T84 cells.
  • Alleviates TNBS-induced rectal allodynia in rats.
  • Alleviates stress-induced colorectal hypersensitivity (CRD) in rats.

Catalog No. 50-003-97003


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