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Apexbio Technology LLC Donepezil HCl 120011-70-3 1g
Supplier: Apexbio Technology LLC B16021000
Donepezil hydrochloride (CAS 120011-70-3) is an acetylcholinesterase (AChE) inhibitor belonging to the piperidine class characterized chemically by an N-benzylpiperidine moiety coupled with an indanone-based group It selectively inhibits AChE with an IC50 of approximately 6 7 nM while its activity toward butyrylcholinesterase (BuChE) is much weaker (IC50 7 4 M) Donepezil hydrochloride is approved by the FDA specifically for Alzheimer s disease (AD) where it has been demonstrated to improve cognitive function in patients with mild to moderate AD symptoms
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