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Apexbio Technology LLC Dorsomorphin (Compound C) 866405-64-3 50mg
Supplier: Apexbio Technology LLC B325250
Dorsomorphin (Compound C CAS 866405-64-3) is a cell-permeable reversible ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) exhibiting a Ki value of 109 nM It displays high specificity towards AMPK relative to related kinases such as protein kinase A protein kinase C and Janus kinase 3 Additionally dorsomorphin acts as an inhibitor of BMP signaling by reducing phosphorylation of Smad1/5/8 leading to inhibited osteogenic differentiation elevated iron levels via decreased hepcidin transcription and enhanced human ESC self-renewal and neural induction
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