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Medchemexpress LLC DOTA-PEG5-C6-DBCO | 94.0% | C49H71N7O14 | 50 MG

Supplier: Medchemexpress LLC HY14031450MG
DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing a DBCO group, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that have Azide groups. PROTACs utilize the intracellular ubiquitin-proteome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains a DBCO group
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Degrades target proteins via the ubiquitin-proteasome system
- Off-white to light yellow solid
- Soluble in DMSO and H2O
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