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Medchemexpress LLC DPTIP | 351353-48-5 | 99.7% | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY131002

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DPTIP is a potent, brain-penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor. It also acts as an exosome inhibitor, demonstrating an IC50 of 30 nM. It is intended for research use only.

  • Potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor
  • Exosome inhibitor
  • IC50 of 30 nM
  • Blocks EV secretion in a dose-dependent manner (0.03-30 μM)
  • Decreases exosome release by 50% in astrocytes at 30 μM
  • Inhibits IL-1β-induced astrocyte-derived EV release in mice (10 mg/kg IP)

Catalog No. 50-003-39504


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